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REVIEW ARTICLE
Year : 2020  |  Volume : 8  |  Issue : 2  |  Page : 101-104

A Review on Exploring the Antibacterial Activity of Cannabinoids with Respect to Biofilm Formation


1 Department of Pediatrics, Gandhi Medical College and Hamidia Hospital, Bhopal, Madhya Pradesh, India
2 Department of Public Health Dentistry, Rishiraj College of Dental Sciences, Bhopal, Madhya Pradesh, India

Correspondence Address:
Dr. Ankita Gupta
Department of Public Health Dentistry, Rishiraj College of Dental Sciences, Bhopal, Madhya Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/JIHS.JIHS_9_20

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Cannabis sativa L is a useful plant as it presents many interesting properties due to its rich metabolic profile such as anti-biofilm and bactericidal action. The metabolite of C. sativa (Cannabinoid) is very potent in treating infectious diseases of bacterial origin. This antibacterial activity is mainly due to the presence of several Cannabinoids like Tetrahydrocannabinol (Δ-8-THC), cannabidiol (CBD), cannabinol (CBN), cannabigerol (CBG), and cannabichromene (CBC). Various studies done in the past have proved that the cannabinoids are active against various Gram-positive and Gram-negative bacteria but there are no published literature related to the effect of cannabinoids on the formation of biofilm. Hence, the present review was conducted with an aim to explore the antibacterial effectiveness of cannabinoid and also its effect on the formation of biofilm.


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