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Year : 2020  |  Volume : 8  |  Issue : 2  |  Page : 83-85

Peripheral Neuropathy: A Rare Side Effect of Metronidazole

1 Department of Pharmacy, Sumandeep Vidyapeeth Deemed to be University, Vadodara, Gujarat, India
2 SBKS Medical Institute and Research Center, Sumandeep Vidyapeeth Deemed to be University, Vadodara, Gujarat, India

Correspondence Address:
Dr. Nisarg Rajeshkumar Hajariwala
Department of Pharmacy, Sumandeep Vidyapeeth Deemed to be University, Pipariya, Waghodiya, Vadodara, Gujarat
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/JIHS.JIHS_19_19

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Metronidazole (MTZ) is a potent drug used against protozoa such as Entamoeba histolytica, Giardia lamblia, Trichomonas vaginalis, and Balantidium coli, anaerobic bacteria, amebic liver abscess, bacterial meningitis, infection of the bone, and infectious disorder of the joint. Common side effects of MTZ include mild abdominal pain, headache, nausea, and persistent metallic taste, while other serious and rare side effects include pseudomembranous colitis, seizures, encephalopathy, and peripheral neuropathy. A case of MTZ-induced peripheral neuropathy has been included in this article. A patient was prescribed MTZ for liver abscess for 4 weeks; the patient developed peripheral neuropathy in 15 days; immediately, he reached the hospital and MTZ was withdrawn. He has then been prescribed pregabalin to treat peripheral neuropathy. The patient improved in 4 days on this treatment and was discharged from the hospital. This study concludes that MTZ has a rare side effect of peripheral neuropathy.

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